Product details
| Product Overview | The product is specific for Adalimumab. This antibody can't block Adalimumab binding with TNF-α in ELISA.Inhibitory IC50 (μg/ml):Non-inhibitory. |
| Description | Adalimumab (Humira) is a humanized monoclonal antibody that’s approved by the U.S. Food and Drug Administration for the treatment of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, chronic psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis. Adalimumab binds to the TNF-α (tumor necrosis factor-alpha), and blocks its interaction with TNF-α receptors, reducing the inflammatory response of autoimmune diseases. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Purification | Protein A affinity column |
| Form | lyophilized |
| Buffer | PBS, pH 7.4, contains 0.02% sodium azide.Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Concentration | 0.5 mg/ml |
| Application | Direct ELISA,
Immunogenicity assay
|
| Immunogen | Adalimumab |
| Conjugate | Unconjugated |
| Clone | 196F3 |
| Storage | The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid freeze/thaw cycles. |